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The key symptom of jaundice is the yellowing of the skin and eyes, which occurs due to an excess of bilirubin in the bloodstream. Bilirubin is a yellow compound that results from the breakdown of red blood cells. When the liver is unable to process bilirubin effectively—due to conditions such as liver disease, bile duct obstruction, or hemolytic anemia—it accumulates in the body, leading to the characteristic yellow tint.

This symptom is significant because it indicates an underlying issue with liver function or the bile system and prompts further evaluation to determine the cause. Other symptoms associated with jaundice can include dark urine and pale stools, but the yellowing of the skin and eyes is the most visually evident and recognized marker for this condition. Understanding this key symptom is essential for recognizing potential liver issues in patients, which can lead to timely diagnosis and treatment.

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