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Thyrotoxicosis refers to a condition characterized by an excessive amount of thyroid hormones in the body, which often results from hyperactivity of the thyroid gland. When the thyroid gland produces an overabundance of thyroid hormones, it leads to a state of increased metabolism and can cause a variety of symptoms, including weight loss, rapid heartbeat, sweating, and nervousness. This condition commonly arises from disorders such as Graves' disease, toxic nodular goiter, or excessive intake of thyroid hormone medication.

Considering the context of the other options: a deficiency of thyroid hormone would be more accurately described by the term hypothyroidism, and a genetic thyroid disorder refers to conditions arising from genetic mutations, which aren't necessarily related to hormone overproduction. An infection of the thyroid gland, known as thyroiditis, does not cause the symptoms associated with thyrotoxicosis and is a separate medical condition altogether. Thus, the definition of thyrotoxicosis aligns specifically with the phenomenon of hyperactivity within the thyroid gland, making it the correct choice.

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