How does keratolytics primarily affect the skin's outer layer?

Keratolytics primarily serve to break down the outer layer of the skin, specifically by softening and destroying the keratin that is present there. This action encourages the shedding of dead skin cells, making it beneficial for conditions that involve thickened skin or excessive scaling, such as psoriasis or calluses. By facilitating the removal of these outer skin layers, keratolytics help to reveal newer, healthier skin underneath, which can enhance the overall appearance and texture of the skin. This process is essential for promoting skin healing and preventing the buildup of damaged cells that may lead to further skin problems.